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Patients should be aware that: No licensed combination product exists in the UK Any combination use would be considered experimental and is not supported by current evidence Clinical decisions must be guided by a qualified healthcare professional with access to current trial data Clinical Evidence and Trial Data Available to UK Patients Retatrutide Phase 2 data showed approximately 24% mean body weight reduction at the highest dose over 48 weeks, but no published trial data exist for the specific cagrilintideretatrutide combination

Q: How often should I get it

When taken as directed, this provides a 1-month supply

The pharmacology of the native IGF-1 system has been characterized in peer-reviewed studies published in the New England Journal of Medicine , Endocrine Reviews , and other top journals, and the IGF-1 LR3 analog has been characterized in the American Journal of Physiology Endocrinology and Metabolism and Drug Testing and Analysis

doi: 10.1038/s42255-021-00402-x 36 MurugathasanMJafariAAmandeepAHassanSAChihataMAbdul-SaterAA